On‐Chip Evaluation of Red Blood Cell Deformability Through Transit Velocity Index in Hematological Diseases
values consistently correlate with RBC characteristics known to enhance deformability-such as thin, elliptical morphology, a high surface-area-to-volume ratio, and low internal viscosity-whereas lower values are associated with characteristics that impair deformability. These findings highlight the impact of RBC characteristics on deformability and the importance of our microfluidic platform as a robust tool for investigating hematological diseases.
Authors
- Tomohito Ohtani (ORCID: https://orcid.org/0000-0002-2963-7895)
- Misato Chimura (ORCID: https://orcid.org/0000-0003-3674-9171)
- Tatsunori Taniguchi (ORCID: https://orcid.org/0009-0004-3434-5864)
- Yasushi Sakata (ORCID: https://orcid.org/0000-0002-5618-4721)
- Chia-Hung Dylan Tsai (ORCID: https://orcid.org/0000-0002-8840-3984)
- Ivan Cimrák (ORCID: https://orcid.org/0000-0002-0389-7891)
- Yasutaka Ueda (ORCID: https://orcid.org/0000-0003-1562-1013)
- Kenji Kajitani
- Shigeo Wada
- Jun‐ichi Nishimura
Institutions
- Osaka Gakuin University (JP)
- National Yang Ming Chiao Tung University (TW)
- University of Žilina (SK)
- The University of Osaka (JP)
Publication Details
- Journal
- Small
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1002/smll.202514520
- Primary Topic
- Blood properties and coagulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00