Enhancing Cross-Patient Seizure Detection with Test-Time Adaptation

Automated seizure detection is essential for effective epilepsy management, yet patient-specific models often generalize poorly across patients due to distribution shifts. Unlike methods focused solely on training-phase generalization, we propose a test-time adaptation strategy that dynamically adjusts model parameters using test samples. Built on ResNet-18, our approach incorporates a learnable consistency loss as an auxiliary objective during training, and introduces adaptive blocks for dynamic updating during testing. Our method has been extensively evaluated on two publicly available datasets, CHB-MIT and Siena, demonstrating strong performance across key metrics. On the CHB-MIT dataset, the proposed approach achieves an accuracy of 95.24%, a sensitivity of 94.69%, and a specificity of 95.85%. Similarly, on the Siena dataset, it attains an accuracy of 91.88%, a sensitivity of 92.32%, and a specificity of 91.59%. These results highlight the promise of test-time adaptation methods for cross-patient seizure detection and provide new insights for future research in this field.

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Publication Details

Journal
International Journal of Neural Systems
Published
2026-04-22
DOI
https://doi.org/10.1142/s0129065726500425
Primary Topic
EEG and Brain-Computer Interfaces
Type
article
Field-Weighted Citation Impact
0.00
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article

Enhancing Cross-Patient Seizure Detection with Test-Time Adaptation

Chenxi Nie, Hailing Feng, Jilong Lian, Yijia Li et al.
International Journal of Neural Systems
EEG and Brain-Computer Interfaces
article

Enhancing Cross-Patient Seizure Detection with Test-Time Adaptation

Chenxi Nie, Hailing Feng, Jilong Lian, Yijia Li, Yanna Zhao, Han Wang
article en

Abstract

Automated seizure detection is essential for effective epilepsy management, yet patient-specific models often generalize poorly across patients due to distribution shifts. Unlike methods focused solely on training-phase generalization, we propose a test-time adaptation strategy that dynamically adjusts model parameters using test samples. Built on ResNet-18, our approach incorporates a learnable consistency loss as an auxiliary objective during training, and introduces adaptive blocks for dynamic updating during testing. Our method has been extensively evaluated on two publicly available datasets, CHB-MIT and Siena, demonstrating strong performance across key metrics. On the CHB-MIT dataset, the proposed approach achieves an accuracy of 95.24%, a sensitivity of 94.69%, and a specificity of 95.85%. Similarly, on the Siena dataset, it attains an accuracy of 91.88%, a sensitivity of 92.32%, and a specificity of 91.59%. These results highlight the promise of test-time adaptation methods for cross-patient seizure detection and provide new insights for future research in this field.

International Journal of Neural Systems
Openalex Percentile: Top 5%
EEG and Brain-Computer Interfaces
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Enhancing Cross-Patient Seizure Detection with Test-Time Adaptation — Chenxi Nie, Hailing Feng, et al. · International Journal of Neural Systems (2026) | TGRS Research Map | TGRS