Neonatal Cerebrovascular Stability Index and Oxygenation With 3-Month Neurodevelopmental Outcomes

BACKGROUND: Limited studies examined associations between proxies of cerebrovascular autoregulation and neurodevelopmental outcomes (NDOs) in congenital heart disease (CHD). OBJECTIVES: ) with 3-month NDOs within CHD and control groups and within CHD subgroups; and 2) group and subgroup differences in these associations. METHODS: with NDOs, and interaction terms examined group and subgroup differences in associations. RESULTS: associated with cognitive scores (P = 0.01) in the cyanotic subgroup. CONCLUSIONS: associated with 3-month cognitive and motor outcomes in CHD and CHD subgroups, and groups differed in their directional associations. Future studies should explore CSI as an indicator of risk for developmental delays in CHD.