QLS5132 Goes after CLDN6 in Ovarian Cancer

ABSTRACT: For patients with advanced platinum-resistant ovarian cancer, treatment options remain limited, but new agents are emerging. One is QLS5132, an antibody-drug conjugate targeting CLDN6; early data from a phase I trial indicates that it has a favorable safety profile and appears active in this disease.

Publication Details

Journal
Cancer Discovery
Published
2026-04-21
DOI
https://doi.org/10.1158/2159-8290.cd-nw2026-0044
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.00
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article

QLS5132 Goes after CLDN6 in Ovarian Cancer

Cancer Discovery
HER2/EGFR in Cancer Research
article

QLS5132 Goes after CLDN6 in Ovarian Cancer

article en

Abstract

ABSTRACT: For patients with advanced platinum-resistant ovarian cancer, treatment options remain limited, but new agents are emerging. One is QLS5132, an antibody-drug conjugate targeting CLDN6; early data from a phase I trial indicates that it has a favorable safety profile and appears active in this disease.

Cancer Discovery
Good health and well-being
Openalex Percentile: Top 9%
HER2/EGFR in Cancer Research
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QLS5132 Goes after CLDN6 in Ovarian Cancer · Cancer Discovery (2026) | TGRS Research Map | TGRS