Expansion of stemlike HIV-specific CD8 <sup>+</sup> T cells and limited viral epitope diversity characterize durable posttreatment control of HIV
T cells and the viral reservoir that are associated with sustained HIV control after ART cessation, informing future immunotherapeutic strategies toward achieving an HIV cure.
Authors
- Itai Muzhingi (ORCID: https://orcid.org/0000-0003-1221-5191)
- Gaurav D. Gaiha (ORCID: https://orcid.org/0000-0001-6875-4472)
- Aljawharah Alrubayyi (ORCID: https://orcid.org/0000-0001-7538-9434)
- Hannah MacLeod
- Charles R. Crain
- Behzad Etemad (ORCID: https://orcid.org/0000-0003-0417-0528)
- Michael J. Peluso (ORCID: https://orcid.org/0000-0003-0585-6230)
- Rachel L. Rutishauser (ORCID: https://orcid.org/0000-0003-3596-059X)
- Anna K. Traunbauer (ORCID: https://orcid.org/0000-0001-9808-9821)
- Steven G. Deeks (ORCID: https://orcid.org/0000-0001-6371-747X)
- Manish C. Choudhary (ORCID: https://orcid.org/0000-0002-3192-7840)
- Gregory M. Laird (ORCID: https://orcid.org/0000-0003-2873-4295)
- J W Li
- Efthimios A Deligiannidis
- R C Deo
- Esther Jeon (ORCID: https://orcid.org/0009-0000-0803-2267)
- Prerana Shrestha (ORCID: https://orcid.org/0009-0008-5998-7571)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- University of California, San Francisco (US)
- Ragon Institute of MGH, MIT and Harvard (US)
- Massachusetts General Hospital (US)
- Harvard–MIT Division of Health Sciences and Technology (US)
- CCC Diagnostics (United States) (US)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- Science Translational Medicine
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1126/scitranslmed.aed0042
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health