Inactivation of MexT in <i>Pseudomonas aeruginosa</i> PAO1 destabilizes cooperation and favors the emergence of a unique quorum sensing variant
, offering insight into evolutionary pressures that select for mutations in quorum-sensing transcription factors and, by extension, a method for bacteria to alter the cohort of genes that are quorum-controlled.
Authors
- Nicole E. Smalley (ORCID: https://orcid.org/0000-0003-3863-4335)
- Ajai A. Dandekar (ORCID: https://orcid.org/0000-0002-2992-6523)
- Maxim Kostylev (ORCID: https://orcid.org/0000-0003-3952-2191)
- E. Peter Greenberg (ORCID: https://orcid.org/0000-0001-9474-8041)
- Kiana R Bellamoroso
Institutions
- University of Washington (US)
Publication Details
- Journal
- Journal of Bacteriology
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1128/jb.00434-25
- Primary Topic
- Bacterial biofilms and quorum sensing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cystic Fibrosis Foundation
- Gilead Sciences
- National Institute of General Medical Sciences
- National Institute of Allergy and Infectious Diseases