Postoperative Pain and Functional Limitations After Corneal Cross-Linking for Keratoconus: A Patient-Reported Outcome Study

BACKGROUND: Keratoconus is a progressive corneal condition that leads to visual impairment and is primarily managed with corneal cross-linking (CXL), a procedure designed to halt its progression. However, while the clinical outcomes of CXL are well-documented, its impact on patient well-being, including postoperative pain and recovery, remains underexplored. This study aimed to evaluate postoperative pain, functional limitations, visual recovery, and patient-reported outcomes following corneal cross-linking (CXL) for keratoconus. METHODS: A structured survey was conducted among 31 patients who underwent CXL for keratoconus. The survey assessed postoperative pain using a Numeric Rating Scale (NRS) and collected information on visual recovery, functional limitations, and the socioeconomic effects of the procedure. Clinical data, including best-corrected visual acuity (BCVA) and keratometry, were also recorded before and after CXL to evaluate the procedure's efficacy. RESULTS: = 0.004). Despite these challenges, 93.5% of participants reported improvement in vision, with most recovering within a week. Objective clinical data supported the effectiveness of the procedure. CONCLUSIONS: Corneal cross-linking is associated with favorable clinical outcomes; however, the early postoperative period is characterized by moderate pain and functional limitations, highlighting the importance of patient-centered care.

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Journal
Life
Published
2026-04-21
DOI
https://doi.org/10.3390/life16040694
Primary Topic
Corneal surgery and disorders
Type
article
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article

Postoperative Pain and Functional Limitations After Corneal Cross-Linking for Keratoconus: A Patient-Reported Outcome Study

Ruta Jaruseviciene, Saulius Galgauskas, Gintare Kirkickaite
Life
Corneal surgery and disorders
article

Postoperative Pain and Functional Limitations After Corneal Cross-Linking for Keratoconus: A Patient-Reported Outcome Study

Ruta Jaruseviciene, Saulius Galgauskas, Gintare Kirkickaite
article en

Abstract

BACKGROUND: Keratoconus is a progressive corneal condition that leads to visual impairment and is primarily managed with corneal cross-linking (CXL), a procedure designed to halt its progression. However, while the clinical outcomes of CXL are well-documented, its impact on patient well-being, including postoperative pain and recovery, remains underexplored. This study aimed to evaluate postoperative pain, functional limitations, visual recovery, and patient-reported outcomes following corneal cross-linking (CXL) for keratoconus. METHODS: A structured survey was conducted among 31 patients who underwent CXL for keratoconus. The survey assessed postoperative pain using a Numeric Rating Scale (NRS) and collected information on visual recovery, functional limitations, and the socioeconomic effects of the procedure. Clinical data, including best-corrected visual acuity (BCVA) and keratometry, were also recorded before and after CXL to evaluate the procedure's efficacy. RESULTS: = 0.004). Despite these challenges, 93.5% of participants reported improvement in vision, with most recovering within a week. Objective clinical data supported the effectiveness of the procedure. CONCLUSIONS: Corneal cross-linking is associated with favorable clinical outcomes; however, the early postoperative period is characterized by moderate pain and functional limitations, highlighting the importance of patient-centered care.

LifeVol. 16(4)
Vilnius University (LT)
Openalex Percentile: Top 14%
Corneal surgery and disorders
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