A cascade model of dynamic cerebral autoregulation
Hb relationship, particularly under forced oscillations during sit-stand, demonstrating the model's physiological relevance. The cascade model provides a mechanistic framework to separate and quantify large- and small-vessel contributions to cerebral blood flow regulation, with potential application in future studies of ageing and cerebrovascular disease.
Authors
- Junyeon Won (ORCID: https://orcid.org/0000-0001-7900-9355)
- Jurgen A.H.R. Claassen (ORCID: https://orcid.org/0000-0002-1778-8151)
- R Zhang
- Takuya Kurazumi (ORCID: https://orcid.org/0000-0001-5218-2414)
- Danilo Cardim (ORCID: https://orcid.org/0000-0002-9261-1321)
- John Ashley
- Kartavya Sharma (ORCID: https://orcid.org/0000-0003-0073-5915)
- Tsubasa Tomoto (ORCID: https://orcid.org/0000-0001-5936-0332)
- Ricardo R. J. Wennekers (ORCID: https://orcid.org/0009-0008-4277-6727)
Institutions
- Nihon University (JP)
- Radboud University Nijmegen (NL)
- Texas Health Dallas (US)
- Radboud University Medical Center (NL)
- Mayo Clinic in Arizona (US)
- Institute for Exercise and Environmental Medicine (US)
- National Institute of Advanced Industrial Science and Technology (JP)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- The Journal of Physiology
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1113/jp290519
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00