Localized delivery of hyaluronic acid-doxorubicin from a surgical paste for post-operative glioblastoma treatment
T cell levels (∗p < 0.5), compared to resected mice. Embedding HA-DOX within Surgiflo™ offers a promising strategy for localized, sustained delivery of chemotherapeutics to the resected cavity, with the potential to improve therapeutic outcomes and minimize systemic toxicity in postoperative glioblastoma treatment.
Authors
- Véronique Préat (ORCID: https://orcid.org/0000-0002-4045-1450)
- Bernard Gallez (ORCID: https://orcid.org/0000-0002-5708-1302)
- Giulia Rodella
- Zhanjun Ma (ORCID: https://orcid.org/0000-0002-0825-0755)
- Riccardo Rampado (ORCID: https://orcid.org/0000-0001-6083-5796)
- Nicolas Joudiou (ORCID: https://orcid.org/0000-0002-6760-7400)
- Kévin Vanvarenberg
- Mariangela Garofalo (ORCID: https://orcid.org/0000-0002-5001-7826)
- Cristiano Pesce (ORCID: https://orcid.org/0000-0001-7789-2877)
- Alessio Malfanti (ORCID: https://orcid.org/0000-0002-3694-8667)
- Mingchao Wang
- Bernard Ucakar
Institutions
- University of Padua (IT)
- UCLouvain (BE)
Publication Details
- Journal
- Materials Today Bio
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1016/j.mtbio.2026.103142
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- EuroNanoMed III
- Fonds De La Recherche Scientifique - FNRS
- Università degli Studi di Padova
- H2020 Marie Skłodowska-Curie Actions