UHPLC–MS/MS Method for the Simultaneous Quantification of 12 Antiretroviral Drugs in Human Plasma Using Dried Sample Spot Devices: Development, Validation, and Stability Evaluation
: The method demonstrated robustness and reproducibility in accordance with FDA and EMA guidelines. It ensures satisfactory accuracy and rapid analysis, supporting its application in clinical practice, including for monitoring the newest long-acting drugs.
Authors
- Marco Simiele
- Amedeo De Nicolò (ORCID: https://orcid.org/0000-0002-5973-9948)
- Alice Palermiti (ORCID: https://orcid.org/0000-0003-0860-280X)
- A D'Avolio
- Jessica Cusato (ORCID: https://orcid.org/0000-0003-1977-9694)
- Greta Sabbia
- Alessandra Manca (ORCID: https://orcid.org/0000-0002-8540-6709)
- Sara Soloperto (ORCID: https://orcid.org/0000-0003-2303-6463)
- Martina Billi (ORCID: https://orcid.org/0009-0000-0210-9913)
- Elisa Barnini
- Camilla Martino
- Gianluca Bianco
- Elisa Martina
Institutions
- University of Turin (IT)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2026-04-21
- DOI
- https://doi.org/10.3390/pharmaceutics18040513
- Primary Topic
- Pharmaceutical Quality and Counterfeiting
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission