Legionella Pneumonia Associated With Rhabdomyolysis and Acute Renal Failure: A Case Report

Legionnaires' disease is a severe form of pneumonia caused by the bacterium Legionella pneumophila. It comprises around 5% of all community-acquired pneumonia, but up to 20% of all severe community-acquired pneumonia. It often presents with extrapulmonary manifestations, including but not limited to myocarditis, hyponatremia, renal failure, and diarrhea, that have increased in incidence over the last few decades. It has a high hospitalization and mortality rate. The Legionella triad of pneumonia, rhabdomyolysis, and acute renal failure, although rare, has even higher mortality rates, especially in vulnerable population groups. Early recognition, diagnosis, and prompt management can help decrease mortality rates and can help reduce costs by preventing admissions to the intensive care unit. We present the case of a man in his 70s with many comorbidities including heart failure, coronary artery disease, atrial fibrillation, and chronic kidney disease who presented with altered mental status, cough, and fevers, developed the Legionella triad, and required care in the intensive care unit, subsequently needing dialysis as an outpatient due to lack of renal recovery as an inpatient, to highlight the importance of prompt multidisciplinary management to improve overall outcomes.

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Publication Details

Journal
Cureus
Published
2026-04-22
DOI
https://doi.org/10.7759/cureus.107537
Primary Topic
Legionella and Acanthamoeba research
Type
article
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article

Legionella Pneumonia Associated With Rhabdomyolysis and Acute Renal Failure: A Case Report

Ravi Siriki, David Kim, Soo Jeong Seo, Kirollos Gerges
Cureus
Legionella and Acanthamoeba research
article

Legionella Pneumonia Associated With Rhabdomyolysis and Acute Renal Failure: A Case Report

Ravi Siriki, David Kim, Soo Jeong Seo, Kirollos Gerges
article en

Abstract

Legionnaires' disease is a severe form of pneumonia caused by the bacterium Legionella pneumophila. It comprises around 5% of all community-acquired pneumonia, but up to 20% of all severe community-acquired pneumonia. It often presents with extrapulmonary manifestations, including but not limited to myocarditis, hyponatremia, renal failure, and diarrhea, that have increased in incidence over the last few decades. It has a high hospitalization and mortality rate. The Legionella triad of pneumonia, rhabdomyolysis, and acute renal failure, although rare, has even higher mortality rates, especially in vulnerable population groups. Early recognition, diagnosis, and prompt management can help decrease mortality rates and can help reduce costs by preventing admissions to the intensive care unit. We present the case of a man in his 70s with many comorbidities including heart failure, coronary artery disease, atrial fibrillation, and chronic kidney disease who presented with altered mental status, cough, and fevers, developed the Legionella triad, and required care in the intensive care unit, subsequently needing dialysis as an outpatient due to lack of renal recovery as an inpatient, to highlight the importance of prompt multidisciplinary management to improve overall outcomes.

Cureus
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Legionella and Acanthamoeba research
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Legionella Pneumonia Associated With Rhabdomyolysis and Acute Renal Failure: A Case Report — Ravi Siriki, David Kim, et al. · Cureus (2026) | TGRS Research Map | TGRS