Clinical Significance of Serum Protein Electrophoresis in Rapid Progression of Multiple Myeloma: A Case Report
: This case highlights that clinically relevant monoclonal gammopathies may arise rapidly in the absence of classical diagnostic features. Routine SPE represents a cost-effective and accessible screening tool that can identify subtle protein abnormalities, prompting the timely use of more specific and invasive diagnostic procedures for aggressive plasma cell disorders.
Authors
- Luigi Michele Pavone (ORCID: https://orcid.org/0000-0002-5145-7428)
- Ylenia Pancione
- Silvia Iannelli
- Pasquale Cocchiaro (ORCID: https://orcid.org/0000-0002-6436-2399)
- Federica Feleppa (ORCID: https://orcid.org/0009-0001-6838-9329)
- Melania Scarcella
- Antonella Cusano
Institutions
- BioClinica (United States) (US)
- Azienda Ospedaliera G.Rummo (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Clinics and Practice
- Published
- 2026-04-21
- DOI
- https://doi.org/10.3390/clinpract16040081
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00