Visible-Light-Driven [3 + 2] Annulation of N-Substituted Aromatic Amines with Nitriles: An Approach to Benzimidazoles
A visible-light-driven [3 + 2] annulation of N-substituted aromatic amines with nitriles has been developed, providing efficient access to benzimidazoles. The reaction proceeds under mild conditions with a broad substrate scope and good functional group tolerance. Mechanistic studies support a photoredox-catalyzed radical pathway.
Authors
- Min Tang (ORCID: https://orcid.org/0000-0002-2218-8409)
- Dongfang Jiang (ORCID: https://orcid.org/0009-0006-3644-7519)
- Xin Xiong
- Hao Dong
- Zhenjie Qi
- Jia Zhou
- Yutong Tang
- Wei-Min He (ORCID: https://orcid.org/0000-0002-9481-6697)
Institutions
- Jining University (CN)
- Hunan University of Technology (CN)
- University of South China (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-04-22
- DOI
- https://doi.org/10.1021/acs.orglett.6c01030
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province