A model for stress analysis of stenosed coronary arteries using the fluid structure interaction method

The bifurcation of the left coronary artery is one of the most critical sites for atherosclerotic plaque development, where rupture initiation can lead to arterial failure and subsequent heart attack. This study aimed to investigate the variation in wall shear stress and von Mises stress at this bifurcation due to plaque formation. A three-dimensional (3D) biomechanical model of a bifurcated coronary artery was developed. Three plaques were modelled for the three branches of the left main (LM), left anterior descending (LAD), and left circumflex (LCx). Fluid-structure interaction models were analysed using the finite element method in ANSYS Fluent. Blood flow was assumed to be laminar, incompressible, and Newtonian in nature. Results showed that wall shear stress peaked at the entrance of the bifurcation in each branch, and both wall shear stress and von Mises stress increased with plaque height. Interestingly, longer plaques were associated with reduced von Mises stress within the arterial wall. These findings provide insight into stress distribution patterns that may contribute to plaque vulnerability and arterial rupture risk.

Authors

Institutions

Publication Details

Journal
Journal of Mechanics in Medicine and Biology
Published
2026-04-22
DOI
https://doi.org/10.1142/s0219519426500363
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A model for stress analysis of stenosed coronary arteries using the fluid structure interaction method

Kamran Hassani, Mohammad Nikkhoo, Mohammad Karimi Zand, Ali Tavakoli Golpaygani
Journal of Mechanics in Medicine and Biology
Coronary Interventions and Diagnostics
article

A model for stress analysis of stenosed coronary arteries using the fluid structure interaction method

Kamran Hassani, Mohammad Nikkhoo, Mohammad Karimi Zand, Ali Tavakoli Golpaygani
article en

Abstract

The bifurcation of the left coronary artery is one of the most critical sites for atherosclerotic plaque development, where rupture initiation can lead to arterial failure and subsequent heart attack. This study aimed to investigate the variation in wall shear stress and von Mises stress at this bifurcation due to plaque formation. A three-dimensional (3D) biomechanical model of a bifurcated coronary artery was developed. Three plaques were modelled for the three branches of the left main (LM), left anterior descending (LAD), and left circumflex (LCx). Fluid-structure interaction models were analysed using the finite element method in ANSYS Fluent. Blood flow was assumed to be laminar, incompressible, and Newtonian in nature. Results showed that wall shear stress peaked at the entrance of the bifurcation in each branch, and both wall shear stress and von Mises stress increased with plaque height. Interestingly, longer plaques were associated with reduced von Mises stress within the arterial wall. These findings provide insight into stress distribution patterns that may contribute to plaque vulnerability and arterial rupture risk.

Journal of Mechanics in Medicine and Biology
Twitter (United States) (US)
Openalex Percentile: Top 11%
Coronary Interventions and Diagnostics
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.