Advancements in artificial intelligence for cancer diagnosis and prognosis prediction: current applications and emerging opportunities

Cancer continues to be a leading cause of mortality worldwide, presenting substantial challenges to public health systems. The traditional approaches to cancer diagnosis and prognosis prediction exhibit certain limitations with respect to accuracy, comprehensiveness, dynamic monitoring, and personalization. With the advancement of artificial intelligence (AI) technologies, novel diagnostic and predictive methods are increasingly addressing these shortcomings. This review provides a comprehensive overview of the primary AI algorithms applied in oncology, including machine learning, deep learning, and large language models. It further examines the distinctive characteristics and appropriate use cases of AI algorithms, highlighting their specific roles in cancer screening, diagnostic accuracy, and outcome forecasting. Additionally, the review discusses emerging trends and persistent challenges, aiming to provide actionable insights that support clinical decision-making and advance scientific innovation in this rapidly evolving field. In conclusion, this review systematically outlines recent advances in AI applications for cancer diagnosis and prognostic prediction, with the objective of facilitating a transformative shift in oncology from experience-based practices toward data-driven precision medicine.

Authors

Institutions

Publication Details

Journal
Frontiers in Cell and Developmental Biology
Published
2026-04-22
DOI
https://doi.org/10.3389/fcell.2026.1769097
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Advancements in artificial intelligence for cancer diagnosis and prognosis prediction: current applications and emerging opportunities

Na Lou, Chen Xue, Qingmiao Shi
Frontiers in Cell and Developmental Biology
AI in cancer detection
article

Advancements in artificial intelligence for cancer diagnosis and prognosis prediction: current applications and emerging opportunities

Na Lou, Chen Xue, Qingmiao Shi
article en

Abstract

Cancer continues to be a leading cause of mortality worldwide, presenting substantial challenges to public health systems. The traditional approaches to cancer diagnosis and prognosis prediction exhibit certain limitations with respect to accuracy, comprehensiveness, dynamic monitoring, and personalization. With the advancement of artificial intelligence (AI) technologies, novel diagnostic and predictive methods are increasingly addressing these shortcomings. This review provides a comprehensive overview of the primary AI algorithms applied in oncology, including machine learning, deep learning, and large language models. It further examines the distinctive characteristics and appropriate use cases of AI algorithms, highlighting their specific roles in cancer screening, diagnostic accuracy, and outcome forecasting. Additionally, the review discusses emerging trends and persistent challenges, aiming to provide actionable insights that support clinical decision-making and advance scientific innovation in this rapidly evolving field. In conclusion, this review systematically outlines recent advances in AI applications for cancer diagnosis and prognostic prediction, with the objective of facilitating a transformative shift in oncology from experience-based practices toward data-driven precision medicine.

Frontiers in Cell and Developmental BiologyVol. 14
National Clinical Research (US), First Affiliated Hospital of Henan University of Science and Technology (CN), First Affiliated Hospital of Zhengzhou University (CN), National Center for Infectious Diseases (US), State Key Laboratory of Diagnosis and Treatment of Infectious Diseases, Zhejiang University (CN)
Openalex Percentile: Top 20%
AI in cancer detection
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Advancements in artificial intelligence for cancer diagnosis and prognosis prediction: current applications and emerging opportunities — Na Lou, Chen Xue, et al. · Frontiers in Cell and Developmental Biology (2026) | TGRS Research Map | TGRS