<i>Vitex agnus-castus</i> extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome.

Objective: gene expression in the ovaries of a rat model of PCOS. Materials and Methods: gene expression. Results: was significantly (p=0.0001) higher in the ovaries of the PCOS group compared to other groups, and consumption of the extract improved the evaluated parameters significantly. Conclusion: The endocrine profile and gene expression were improved in the rat ovary following administration of VE, and therefore, the therapeutic effect of VE may be expected in PCOS.