State Space Clustering for Interpretable Fetal Heart Rate Characterization

Computerized cardiotocography (CTG) often relies on fetal heart rate (FHR) features with weak correlations to umbilical cord blood pH, the gold standard for neonatal acidosis, whereas deep learning features lack interpretability. In this work, we propose a novel family of interpretable FHR features based on clustering state vectors from shadow manifolds reconstructed from FHR signals. This approach partitions recordings into low- and high-volatility regimes and derives features that quantify both cluster compactness and separation. Experiments on an open-access CTG database demonstrate that these features achieve substantially stronger correlations with cord blood pH than conventional variability and nonlinear measures, which indicates their potential to improve the diagnostic power of computerized FHR analysis.

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Publication Details

Published
2026-04-21
DOI
https://doi.org/10.1109/icassp55912.2026.11462144
Primary Topic
Neonatal and fetal brain pathology
Type
article
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article

State Space Clustering for Interpretable Fetal Heart Rate Characterization

Cassandra Heiselman, Petar M. Djurić, Guanchao Feng, Kurt Butler et al.
Neonatal and fetal brain pathology
article

State Space Clustering for Interpretable Fetal Heart Rate Characterization

Cassandra Heiselman, Petar M. Djurić, Guanchao Feng, Kurt Butler, T A Chen
article en

Abstract

Computerized cardiotocography (CTG) often relies on fetal heart rate (FHR) features with weak correlations to umbilical cord blood pH, the gold standard for neonatal acidosis, whereas deep learning features lack interpretability. In this work, we propose a novel family of interpretable FHR features based on clustering state vectors from shadow manifolds reconstructed from FHR signals. This approach partitions recordings into low- and high-volatility regimes and derives features that quantify both cluster compactness and separation. Experiments on an open-access CTG database demonstrate that these features achieve substantially stronger correlations with cord blood pH than conventional variability and nonlinear measures, which indicates their potential to improve the diagnostic power of computerized FHR analysis.

Cleveland Clinic (US), Stony Brook University (US), University of Edinburgh (GB)
Zero hunger
Openalex Percentile: Top 19%
Neonatal and fetal brain pathology
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State Space Clustering for Interpretable Fetal Heart Rate Characterization — Cassandra Heiselman, Petar M. Djurić, et al. · (2026) | TGRS Research Map | TGRS