Electromagnetic field induced activation of amyloid-β degrading enzyme, neprilysin, for accelerated Alzheimer's disease therapy
, indicating significantly accelerated enzyme activity and improved amyloid-β degradation potential.ConclusionsThe integrated model shows that optimized EM stimulation enhances enzyme-mediated amyloid-β degradation by lowering energy barriers and increasing reaction rates, supporting a potential noninvasive therapeutic strategy for AD.
Authors
- Sohom Bhattacharjee (ORCID: https://orcid.org/0000-0001-8705-1473)
- Yash Shah (ORCID: https://orcid.org/0000-0002-7393-1469)
- Abdul Hadee (ORCID: https://orcid.org/0000-0002-1449-5337)
- Choon Silk Cho
- Jeeln Choi
- Moon Que Lee
- MinYoung Kim
Institutions
- University of Seoul (KR)
- Korea Aerospace University (KR)
- CHA University (KR)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1177/13872877261444315
- Primary Topic
- Electromagnetic Fields and Biological Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00