Periodontal Disease and Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis of Risk and Survival Outcomes

appears to be an adverse prognostic marker. These findings underscore the relevance of periodontal inflammation and microbial factors across the OSCC continuum, from carcinogenesis to clinical outcomes, and support their consideration as potential targets for risk stratification and prevention strategies.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-21
DOI
https://doi.org/10.3390/jcm15083161
Primary Topic
Oral microbiology and periodontitis research
Type
article
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Periodontal Disease and Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis of Risk and Survival Outcomes

Carlos Enrique Cuevas‐Suárez, Abigailt Flores‐Ledesma, Andrea Ordóñez Balladares, Luis Chauca-Bajaña et al.
Journal of Clinical Medicine
Oral microbiology and periodontitis research
article

Periodontal Disease and Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis of Risk and Survival Outcomes

Carlos Enrique Cuevas‐Suárez, Abigailt Flores‐Ledesma, Andrea Ordóñez Balladares, Luis Chauca-Bajaña, Gina Fernanda Vásquez Armas, Gabriela Guadalupe Zambrano Manzaba, Carlos Andrés Guim Martínez, Byron Velasquez Ron, Veronica Natalia Maroto Hidalgo, Sara Isabel Marcalupo Llerena
article en

Abstract

appears to be an adverse prognostic marker. These findings underscore the relevance of periodontal inflammation and microbial factors across the OSCC continuum, from carcinogenesis to clinical outcomes, and support their consideration as potential targets for risk stratification and prevention strategies.

Journal of Clinical MedicineVol. 15(8)
Universidad Autónoma del Estado de Hidalgo (MX), Central University of Ecuador (EC), University of Guayaquil (EC), Universidad Católica de Santiago de Guayaquil (EC), Universidad de Las Américas (EC), Benemérita Universidad Autónoma de Puebla (MX)
No poverty
Openalex Percentile: Top 16%
Oral microbiology and periodontitis research
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