Cell-type-resolved transcriptomic landscape of human focal cortical dysplasia
in endothelial cells. These results link cell-type-specific transcriptional programs to histopathological heterogeneity across FCD subtypes, identify candidate tissue-detectable markers, and provide insight into nonneuronal contributions to epileptogenic cortical malformations.
Authors
- Chuantao Fang (ORCID: https://orcid.org/0000-0002-5876-3882)
- Y F LIU (ORCID: https://orcid.org/0000-0001-7074-0272)
- Jingjing Guo (ORCID: https://orcid.org/0000-0002-3808-900X)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Haojie Lu (ORCID: https://orcid.org/0000-0003-3477-7662)
- Dashi Qi (ORCID: https://orcid.org/0000-0002-0614-7068)
- Yanfeng Tan (ORCID: https://orcid.org/0009-0000-0884-7562)
- Guilin Meng
- Rongliang Guo
- Rui Zhao (ORCID: https://orcid.org/0009-0004-9444-571X)
- Xianming Liu
- Ziwu Wang
Institutions
- Hebei University of Engineering (CN)
- Chinese Academy of Tropical Agricultural Sciences (CN)
- Tongji University (CN)
- Fudan University (CN)
- Shanghai Ninth People's Hospital (CN)
- Tongren Hospital (CN)
- Shanghai Tenth People's Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Center for Clinical Research (United States) (US)
- Children's Hospital of Fudan University (CN)
- Shanghai Children's Hospital (CN)
- Yangpu Hospital of Tongji University (CN)
- Universidade de Vigo (ES)
Publication Details
- Journal
- Proceedings of the National Academy of Sciences
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1073/pnas.2513674123
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China