Advancing models of survivorship care research: an overview and recommendations for future studies

The growing population of cancer survivors underscores the need for models of care that effectively address their long-term needs. Over recent decades, various models have been proposed, but guidance regarding their development, testing, implementation, and evaluation remains limited. To address this gap, we conducted an overview of randomized controlled trials (RCTs) that assessed survivorship care models (1) to identify common features and methodological gaps; and (2) to assess how these models contribute to improving survivorship care by mapping their pre-defined endpoints to the quality domains of the Quality of Cancer Survivorship Care Framework and the goals of the Quintuple Aim. Lastly, we provide recommendations for future studies, specifically focusing on clarifying terminology, adopting trial methods that move beyond standard comparative designs, expanding research to more diverse populations and settings, and incorporating endpoints that capture both high-quality care and broader health system performance.

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Publication Details

Journal
JNCI Journal of the National Cancer Institute
Published
2026-04-17
DOI
https://doi.org/10.1093/jnci/djag123
Primary Topic
Cancer survivorship and care
Type
article
Field-Weighted Citation Impact
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article

Advancing models of survivorship care research: an overview and recommendations for future studies

Larissa Nekhlyudov, J. Vos, Karolina Lisy, Michael Jefford et al.
JNCI Journal of the National Cancer Institute
Cancer survivorship and care
article

Advancing models of survivorship care research: an overview and recommendations for future studies

Larissa Nekhlyudov, J. Vos, Karolina Lisy, Michael Jefford, Daan Brandenbarg, Raymond J Chan, Jon Emery
article en

Abstract

The growing population of cancer survivors underscores the need for models of care that effectively address their long-term needs. Over recent decades, various models have been proposed, but guidance regarding their development, testing, implementation, and evaluation remains limited. To address this gap, we conducted an overview of randomized controlled trials (RCTs) that assessed survivorship care models (1) to identify common features and methodological gaps; and (2) to assess how these models contribute to improving survivorship care by mapping their pre-defined endpoints to the quality domains of the Quality of Cancer Survivorship Care Framework and the goals of the Quintuple Aim. Lastly, we provide recommendations for future studies, specifically focusing on clarifying terminology, adopting trial methods that move beyond standard comparative designs, expanding research to more diverse populations and settings, and incorporating endpoints that capture both high-quality care and broader health system performance.

JNCI Journal of the National Cancer Institute
Brigham and Women's Hospital (US), University Medical Center Groningen (NL), The University of Melbourne (AU), Flinders University (AU), Nanyang Technological University (SG), Dutch Cancer Society (NL), Peter MacCallum Cancer Centre (AU), Amsterdam Neuroscience (NL), Amsterdam University Medical Centers (NL), University of Amsterdam (NL)
Good health and well-being
Openalex Percentile: Top 17%
Cancer survivorship and care
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