Radical Cascade Sulfonylation/Cyclization of 1-Acryloyl-2-cyanoindoles/2-Cyano- <i>N</i> -arylacrylamides with Aryldiazonium Tetrafluoroborates via the Insertion of Sulfur Dioxide
serves as a dual-function reagent, acting as both a reducing agent and a sulfur dioxide surrogate for the generation of sulfonyl radicals, which underwent a cascade sequence, including radical addition to the C═C bonds, intramolecular cyclization, and hydrolysis to deliver the final products.
Authors
- Jian-Hong Fan (ORCID: https://orcid.org/0009-0009-0136-8281)
- Yu Liu (ORCID: https://orcid.org/0000-0003-4555-8238)
- Yuan Luo (ORCID: https://orcid.org/0009-0000-1193-4923)
Institutions
- Hunan Institute of Science and Technology (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1021/acs.joc.6c00164
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hunan Province