Pedunculated Acral Keratotic Papule on an Ischemic Foot

An 86-year-old man presented with a slowly enlarging, subject to chronic mechanical irritation, pedunculated keratotic papule on the plantar tip of the right hallux in the setting of severe peripheral arterial disease. Excision was deferred until after endovascular revascularization to reduce the risk of nonhealing and limb complications, after which the lesion was removed without wound sequelae. Histopathology demonstrated a conical papule with a central collagenous core and an overlying cap of compact hyperkeratosis. This case highlights key clinicopathologic features that distinguish acral keratotic tumors and underscores the importance of perfusion optimization when planning elective excision on an ischemic limb.

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Publication Details

Journal
Dermatopathology
Published
2026-04-21
DOI
https://doi.org/10.3390/dermatopathology13020018
Primary Topic
Genetic and rare skin diseases.
Type
article
Field-Weighted Citation Impact
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article

Pedunculated Acral Keratotic Papule on an Ischemic Foot

Joshua M. Schulman, Janmesh Patel, Sara Dahle, Pooja A. Shet et al.
Dermatopathology
Genetic and rare skin diseases.
article

Pedunculated Acral Keratotic Papule on an Ischemic Foot

Joshua M. Schulman, Janmesh Patel, Sara Dahle, Pooja A. Shet, Marat D. Kazak
article en

Abstract

An 86-year-old man presented with a slowly enlarging, subject to chronic mechanical irritation, pedunculated keratotic papule on the plantar tip of the right hallux in the setting of severe peripheral arterial disease. Excision was deferred until after endovascular revascularization to reduce the risk of nonhealing and limb complications, after which the lesion was removed without wound sequelae. Histopathology demonstrated a conical papule with a central collagenous core and an overlying cap of compact hyperkeratosis. This case highlights key clinicopathologic features that distinguish acral keratotic tumors and underscores the importance of perfusion optimization when planning elective excision on an ischemic limb.

DermatopathologyVol. 13(2)
VA Northern California Health Care System (US), University of California Davis Medical Center (US)
Good health and well-being
Openalex Percentile: Top 9%
Genetic and rare skin diseases.
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