Rethinking Vitamin A Deficiency: Its Causes, Ophthalmologic Presentation, and Management Gaps at a New England Tertiary Hospital

: In this high-resource clinical setting, VAD is common in an at-risk population and largely driven by nutrition-related disease states affecting absorption, metabolism, and hepatic storage. Despite clear biochemical deficiency and associated mortality risk, VAD is underrecognized, undertreated, and infrequently linked to ocular evaluation, highlighting a critical gap in nutrition-focused screening, interdisciplinary communication, and proactive vitamin A assessment in medically complex adults.

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Publication Details

Journal
Nutrients
Published
2026-04-21
DOI
https://doi.org/10.3390/nu18081310
Primary Topic
Antioxidant Activity and Oxidative Stress
Type
article
Field-Weighted Citation Impact
0.00
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article

Rethinking Vitamin A Deficiency: Its Causes, Ophthalmologic Presentation, and Management Gaps at a New England Tertiary Hospital

Michael E. Zegans, Shannon L. Kelleher, Corbin M. Dameron, Katherine H. Fearon et al.
Nutrients
Antioxidant Activity and Oxidative Stress
article

Rethinking Vitamin A Deficiency: Its Causes, Ophthalmologic Presentation, and Management Gaps at a New England Tertiary Hospital

Michael E. Zegans, Shannon L. Kelleher, Corbin M. Dameron, Katherine H. Fearon, Amer Al-Nimr
article en

Abstract

: In this high-resource clinical setting, VAD is common in an at-risk population and largely driven by nutrition-related disease states affecting absorption, metabolism, and hepatic storage. Despite clear biochemical deficiency and associated mortality risk, VAD is underrecognized, undertreated, and infrequently linked to ocular evaluation, highlighting a critical gap in nutrition-focused screening, interdisciplinary communication, and proactive vitamin A assessment in medically complex adults.

NutrientsVol. 18(8)
Dartmouth–Hitchcock Medical Center (US), University of Massachusetts Lowell (US)
Zero hunger
Openalex Percentile: Top 20%
Antioxidant Activity and Oxidative Stress
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