Robust Proteinosomes with PEG Protein Mixed Corona for Enhanced Protection against Extreme pH Conditions and Trypsin Digestion

) self-assembled into proteinosomes consisting of a PDEGMA membrane and a PEG protein mixed corona at temperatures above their lower critical solution temperatures. The activities of enzymes in all the proteinosomes were well preserved, and the mixed corona proteinosomes exhibited more effective protection against extreme pH conditions and trypsin digestion than the regular ones.

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Publication Details

Journal
Biomacromolecules
Published
2026-04-21
DOI
https://doi.org/10.1021/acs.biomac.5c02616
Primary Topic
Proteins in Food Systems
Type
article
Field-Weighted Citation Impact
0.00

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article

Robust Proteinosomes with PEG Protein Mixed Corona for Enhanced Protection against Extreme pH Conditions and Trypsin Digestion

Yue Zhang, Liyuan Tian, Yue Wang
Biomacromolecules
Proteins in Food Systems
article

Robust Proteinosomes with PEG Protein Mixed Corona for Enhanced Protection against Extreme pH Conditions and Trypsin Digestion

Yue Zhang, Liyuan Tian, Yue Wang
article en

Abstract

) self-assembled into proteinosomes consisting of a PDEGMA membrane and a PEG protein mixed corona at temperatures above their lower critical solution temperatures. The activities of enzymes in all the proteinosomes were well preserved, and the mixed corona proteinosomes exhibited more effective protection against extreme pH conditions and trypsin digestion than the regular ones.

BiomacromoleculesVol. 27(5)
Hebei University of Technology (CN), Institute of Polymers (BG), Ingenierie des Materiaux polymeres (FR)
Natural Science Foundation of Hebei Province
Zero hunger
Openalex Percentile: Top 22%
Proteins in Food Systems
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