Epigenetic and Transcriptomic Pathways Underlying Animal Models of Cognitive and Psychiatric Disorders: A Scoping Review

The specific convergence of epigenetic disruptions in neural circuits involved in synaptic structure and inhibitory function could play a role in the generation of neuropsychiatric phenotypes in animal models, highlighting the importance of circuit- and cell-type-specific epigenetics while pointing to potential therapeutic avenues.

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Publication Details

Journal
Current Issues in Molecular Biology
Published
2026-04-21
DOI
https://doi.org/10.3390/cimb48040425
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
0.00
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article

Epigenetic and Transcriptomic Pathways Underlying Animal Models of Cognitive and Psychiatric Disorders: A Scoping Review

Ajay Pal, Jaishriram Rathored, Deepika Sai Painkra
Current Issues in Molecular Biology
Epigenetics and DNA Methylation
article

Epigenetic and Transcriptomic Pathways Underlying Animal Models of Cognitive and Psychiatric Disorders: A Scoping Review

Ajay Pal, Jaishriram Rathored, Deepika Sai Painkra
article en

Abstract

The specific convergence of epigenetic disruptions in neural circuits involved in synaptic structure and inhibitory function could play a role in the generation of neuropsychiatric phenotypes in animal models, highlighting the importance of circuit- and cell-type-specific epigenetics while pointing to potential therapeutic avenues.

Current Issues in Molecular BiologyVol. 48(4)
Datta Meghe Institute of Higher Education and Research (IN), Temple University (US)
Openalex Percentile: Top 17%
Epigenetics and DNA Methylation
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