Real-World Antiplatelet Use and Clinical Outcomes in Patients with Advanced Chronic Kidney Disease Following Acute Coronary Syndrome: A Descriptive Cohort Study

In this real-world cohort of patients with advanced CKD and ESRD following ACS, a substantial burden of mortality, recurrent ischemic events, and bleeding complications was observed, underscoring the narrow therapeutic window in this high-risk population. These findings are descriptive and hypothesis-generating, supporting the need for individualized antiplatelet strategies and prospective studies specifically enrolling patients with advanced CKD.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-21
DOI
https://doi.org/10.3390/jcm15083167
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
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article

Real-World Antiplatelet Use and Clinical Outcomes in Patients with Advanced Chronic Kidney Disease Following Acute Coronary Syndrome: A Descriptive Cohort Study

Majed Almutairi, Mansour Alomran, Amani Alsubaie, Lama Alfehaid et al.
Journal of Clinical Medicine
Antiplatelet Therapy and Cardiovascular Diseases
article

Real-World Antiplatelet Use and Clinical Outcomes in Patients with Advanced Chronic Kidney Disease Following Acute Coronary Syndrome: A Descriptive Cohort Study

Majed Almutairi, Mansour Alomran, Amani Alsubaie, Lama Alfehaid, Saleh Alghadeer, Eman Alzahrani
article en

Abstract

In this real-world cohort of patients with advanced CKD and ESRD following ACS, a substantial burden of mortality, recurrent ischemic events, and bleeding complications was observed, underscoring the narrow therapeutic window in this high-risk population. These findings are descriptive and hypothesis-generating, supporting the need for individualized antiplatelet strategies and prospective studies specifically enrolling patients with advanced CKD.

Journal of Clinical MedicineVol. 15(8)
King Saud bin Abdulaziz University for Health Sciences (SA), King Abdulaziz Medical City (SA), King Abdullah International Medical Research Center (SA)
Good health and well-being
Openalex Percentile: Top 19%
Antiplatelet Therapy and Cardiovascular Diseases
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Real-World Antiplatelet Use and Clinical Outcomes in Patients with Advanced Chronic Kidney Disease Following Acute Coronary Syndrome: A Descriptive Cohort Study — Majed Almutairi, Mansour Alomran, et al. · Journal of Clinical Medicine (2026) | TGRS Research Map | TGRS