Direct Immunotherapy Injection Shrinks Oral Precancers

ABSTRACT: In a phase I clinical trial, patients with oral precancers who received immunotherapy injected directly into their lesions experienced tumor shrinkage and no dose-limiting toxicities. The findings suggest that immunotherapy could play a role in cancer prevention.

Publication Details

Journal
Cancer Discovery
Published
2026-04-21
DOI
https://doi.org/10.1158/2159-8290.cd-nw2026-0043
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Direct Immunotherapy Injection Shrinks Oral Precancers

Cancer Discovery
Cancer Immunotherapy and Biomarkers
article

Direct Immunotherapy Injection Shrinks Oral Precancers

article en

Abstract

ABSTRACT: In a phase I clinical trial, patients with oral precancers who received immunotherapy injected directly into their lesions experienced tumor shrinkage and no dose-limiting toxicities. The findings suggest that immunotherapy could play a role in cancer prevention.

Cancer Discovery
Good health and well-being
Openalex Percentile: Top 10%
Cancer Immunotherapy and Biomarkers
DOISourceOpenAlex
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