Comparison of <i>in vitro</i> antibiotic susceptibility testing of <i>R. typhi</i> using plaque assay and quantitative real-time PCR
infection (doxycycline and azithromycin), along with amoxicillin as a negative control. Both showed comparable results for all antibiotics tested, further supporting nucleic acid detection as a reliable and faster alternative.
Authors
- Mavuto Mukaka (ORCID: https://orcid.org/0000-0002-5036-6583)
- Weerawat Phuklia (ORCID: https://orcid.org/0000-0003-1468-5138)
- Matthew T. Robinson (ORCID: https://orcid.org/0000-0003-1187-2712)
- Mayfong Mayxay (ORCID: https://orcid.org/0000-0002-6056-4516)
- Christina M. Farris (ORCID: https://orcid.org/0000-0002-4004-410X)
- Nicholas Day (ORCID: https://orcid.org/0000-0003-2309-1171)
- Allen L. Richards (ORCID: https://orcid.org/0000-0002-1065-429X)
- Koukeo Phommasone (ORCID: https://orcid.org/0000-0002-3814-0522)
- Elizabeth A. Ashley (ORCID: https://orcid.org/0000-0002-7620-4822)
- Paul N. Newton (ORCID: https://orcid.org/0000-0003-0734-2022)
- Kaisone Padith
Institutions
- Naval Medical Research Command (US)
- Mahidol University (TH)
- Mahosot Hospital (LA)
- Angkor Hospital for Children (KH)
- University of Oxford (GB)
- Richard Wolf (Germany) (DE)
- Mahidol Oxford Tropical Medicine Research Unit (TH)
- Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LA)
- Ministry of Health (VN)
- University of Health Sciences (SO)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1128/spectrum.03595-25
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust