Edge-Native Intelligence for Sovereign Life Science Data: Architecture Patterns for Genomic Research at the Computational Frontier

Position paper arguing for edge-native architecture as the default for sovereign life science data processing. Proposes the LQM-to-SQM intelligence progression for genomic AI, contextualises within DRAGEN and Clara Parabricks, and frames data sovereignty as architectural necessity. Extends the Reality Construct framework (Waern, 2026).

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-04-21
DOI
https://doi.org/10.5281/zenodo.19683118
Primary Topic
Scientific Computing and Data Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Edge-Native Intelligence for Sovereign Life Science Data: Architecture Patterns for Genomic Research at the Computational Frontier

Nicolas Waern
Zenodo (CERN European Organization for Nuclear Research)
Scientific Computing and Data Management
article

Edge-Native Intelligence for Sovereign Life Science Data: Architecture Patterns for Genomic Research at the Computational Frontier

Nicolas Waern
article en

Abstract

Position paper arguing for edge-native architecture as the default for sovereign life science data processing. Proposes the LQM-to-SQM intelligence progression for genomic AI, contextualises within DRAGEN and Clara Parabricks, and frames data sovereignty as architectural necessity. Extends the Reality Construct framework (Waern, 2026).

Zenodo (CERN European Organization for Nuclear Research)
Association of British Orchestras (GB)
Responsible consumption and production
Openalex Percentile: Top 4%
Scientific Computing and Data Management
DOIOpen Access PDFOpenAlex
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Edge-Native Intelligence for Sovereign Life Science Data: Architecture Patterns for Genomic Research at the Computational Frontier — Nicolas Waern · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS