Rifampin resistance and multidrug resistance or extensive drug resistance (MDR/XDR) predict failure in monomicrobial <i>Staphylococcus epidermidis</i> periprosthetic joint infection (PJI) – a 15-year single-center cohort study

PJIs represent higher-risk infections and should prompt early optimization of biofilm-active therapy and surgical source control. Univariable analysis confirmed rifampin resistance; levofloxacin resistance; and, in particular, their combination as strong predictors of treatment failure.

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Publication Details

Journal
Journal of Bone and Joint Infection
Published
2026-04-21
DOI
https://doi.org/10.5194/jbji-11-237-2026
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

Rifampin resistance and multidrug resistance or extensive drug resistance (MDR/XDR) predict failure in monomicrobial Staphylococcus epidermidis periprosthetic joint infection (PJI) – a 15-year single-center cohort study

Santiago Gabardo, Álvaro Auñón, Javier Sanado, Jaime Esteban et al.
Journal of Bone and Joint Infection
Orthopedic Infections and Treatments
article

Rifampin resistance and multidrug resistance or extensive drug resistance (MDR/XDR) predict failure in monomicrobial Staphylococcus epidermidis periprosthetic joint infection (PJI) – a 15-year single-center cohort study

Santiago Gabardo, Álvaro Auñón, Javier Sanado, Jaime Esteban, Ricardo de la Concha, Carmen Álvaro
article en

Abstract

PJIs represent higher-risk infections and should prompt early optimization of biofilm-active therapy and surgical source control. Univariable analysis confirmed rifampin resistance; levofloxacin resistance; and, in particular, their combination as strong predictors of treatment failure.

Journal of Bone and Joint InfectionVol. 11(2)
Centre for Biomedical Network Research on Rare Diseases (ES), Hospital Universitario Fundación Jiménez Díaz (ES), Medical Research Network (US)
Good health and well-being
Openalex Percentile: Top 20%
Orthopedic Infections and Treatments
DOIOpen Access PDFOpenAlex
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