Impact of Allergic Diseases or Obstructive Sleep Apnea Risk on Severe Mycoplasma pneumoniae Pneumonia in Children: A Clinical Study and Nomogram Construction

: Children with MPP and comorbid AD or OSA risk are more likely to develop SMPP. Among children aged 6-12 years, RQLQ score is positively correlated with the severity of MPP. AD, PSQ score, LDH, and ferritin are independent risk factors for SMPP. Clinicians should be alert to the development of SMPP when children with MPP present with a history of AD, PSQ score >3.5, LDH >327.50 U/L, or ferritin >120.05 ng/mL. The visual nomogram model constructed by combining these risk factors demonstrates improved predictive performance for SMPP, with high predictive efficacy and accuracy. It has great clinical value and can be used for individualized risk assessment and early intervention. However, our proposed nomogram requires external validation prior to broader implementation.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-21
DOI
https://doi.org/10.3390/jcm15083159
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
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article

Impact of Allergic Diseases or Obstructive Sleep Apnea Risk on Severe Mycoplasma pneumoniae Pneumonia in Children: A Clinical Study and Nomogram Construction

Tienan Feng, Mengting Zhang, Z-F Yu, Song Jingrong et al.
Journal of Clinical Medicine
Pneumonia and Respiratory Infections
article

Impact of Allergic Diseases or Obstructive Sleep Apnea Risk on Severe Mycoplasma pneumoniae Pneumonia in Children: A Clinical Study and Nomogram Construction

Tienan Feng, Mengting Zhang, Z-F Yu, Song Jingrong, Ruimeng Ma, Shuping Jin, Yu Fu, Rui Li, Xiaoying Zhang
article en

Abstract

: Children with MPP and comorbid AD or OSA risk are more likely to develop SMPP. Among children aged 6-12 years, RQLQ score is positively correlated with the severity of MPP. AD, PSQ score, LDH, and ferritin are independent risk factors for SMPP. Clinicians should be alert to the development of SMPP when children with MPP present with a history of AD, PSQ score >3.5, LDH >327.50 U/L, or ferritin >120.05 ng/mL. The visual nomogram model constructed by combining these risk factors demonstrates improved predictive performance for SMPP, with high predictive efficacy and accuracy. It has great clinical value and can be used for individualized risk assessment and early intervention. However, our proposed nomogram requires external validation prior to broader implementation.

Journal of Clinical MedicineVol. 15(8)
Shanghai Jiao Tong University (CN), Shanghai Ninth People's Hospital (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 16%
Pneumonia and Respiratory Infections
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