Ultra-high dose rate dependent modeling of plasmid DNA damage with TOPAS-nBio
. These results suggest that the reduction in DNA damage observed experimentally at low DNA concentrations and low scavenging capacities is due to the intertrack effect, with no difference predicted at low DNA concentrations and cell-like scavenging capacities.
Authors
- Jay A. LaVerne (ORCID: https://orcid.org/0000-0002-8383-7476)
- Bruce Faddegon (ORCID: https://orcid.org/0000-0002-4573-1582)
- Jan Schuemann (ORCID: https://orcid.org/0000-0002-7554-8818)
- Wook‐Geun Shin (ORCID: https://orcid.org/0000-0002-8622-1888)
- Harald Paganetti (ORCID: https://orcid.org/0000-0002-6257-2413)
- Mohammad Rezaee (ORCID: https://orcid.org/0000-0003-4607-9570)
- Thongchai A M Masilela (ORCID: https://orcid.org/0000-0002-1717-6761)
- J Naoki D-Kondo (ORCID: https://orcid.org/0000-0002-4410-1925)
- Jose Asuncion Ramos-Mendez (ORCID: https://orcid.org/0000-0002-8106-5142)
Institutions
- University of Notre Dame (US)
- Harvard University (US)
- Johns Hopkins University (US)
- University of California, San Francisco (US)
- Johns Hopkins Medicine (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Physics in Medicine and Biology
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1088/1361-6560/ae62c6
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00