Dysregulated Efferocytosis and Immune Microenvironment in High Somatic Cell Count Dairy Cows

T cell, indicating a pro-inflammatory immune microenvironment. Our study highlights the dysregulation of efferocytosis and immune microenvironment in milk cells of high SCC cows, potentially contributing to chronic inflammation and impaired mammary gland health. Reviving proper efferocytic function and rebalancing the immune microenvironment are essential for enhancing disease management and improving dairy cow welfare and productivity. Understanding the significance of milk cells in udder health can facilitate targeted interventions to optimise milk production and maintain mammary health in dairy farming.

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Publication Details

Journal
Journal of Animal Physiology and Animal Nutrition
Published
2026-04-21
DOI
https://doi.org/10.1111/jpn.70066
Primary Topic
Milk Quality and Mastitis in Dairy Cows
Type
article
Field-Weighted Citation Impact
0.00

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article

Dysregulated Efferocytosis and Immune Microenvironment in High Somatic Cell Count Dairy Cows

Diming Wang, J Cai, Juan Feng, Mengmeng Deng et al.
Journal of Animal Physiology and Animal Nutrition
Milk Quality and Mastitis in Dairy Cows
article

Dysregulated Efferocytosis and Immune Microenvironment in High Somatic Cell Count Dairy Cows

Diming Wang, J Cai, Juan Feng, Mengmeng Deng, Jianxin Liu, Feixiang Fan
article en

Abstract

T cell, indicating a pro-inflammatory immune microenvironment. Our study highlights the dysregulation of efferocytosis and immune microenvironment in milk cells of high SCC cows, potentially contributing to chronic inflammation and impaired mammary gland health. Reviving proper efferocytic function and rebalancing the immune microenvironment are essential for enhancing disease management and improving dairy cow welfare and productivity. Understanding the significance of milk cells in udder health can facilitate targeted interventions to optimise milk production and maintain mammary health in dairy farming.

Journal of Animal Physiology and Animal Nutrition
Ministry of Agriculture (LV), Zhejiang University (CN)
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 9%
Milk Quality and Mastitis in Dairy Cows
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Dysregulated Efferocytosis and Immune Microenvironment in High Somatic Cell Count Dairy Cows — Diming Wang, J Cai, et al. · Journal of Animal Physiology and Animal Nutrition (2026) | TGRS Research Map | TGRS