Dysregulated Efferocytosis and Immune Microenvironment in High Somatic Cell Count Dairy Cows
T cell, indicating a pro-inflammatory immune microenvironment. Our study highlights the dysregulation of efferocytosis and immune microenvironment in milk cells of high SCC cows, potentially contributing to chronic inflammation and impaired mammary gland health. Reviving proper efferocytic function and rebalancing the immune microenvironment are essential for enhancing disease management and improving dairy cow welfare and productivity. Understanding the significance of milk cells in udder health can facilitate targeted interventions to optimise milk production and maintain mammary health in dairy farming.
Authors
- Diming Wang (ORCID: https://orcid.org/0000-0002-1451-6863)
- J Cai
- Juan Feng
- Mengmeng Deng
- Jianxin Liu (ORCID: https://orcid.org/0000-0002-5812-5186)
- Feixiang Fan
Institutions
- Ministry of Agriculture (LV)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of Animal Physiology and Animal Nutrition
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1111/jpn.70066
- Primary Topic
- Milk Quality and Mastitis in Dairy Cows
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China