A Rare Association of Emphysematous Gastritis With Gastric Adenocarcinoma: A Case Report and Diagnostic Pitfalls

Emphysematous gastritis is a rare and life-threatening condition characterized by the presence of gas within the gastric wall, typically caused by gas-forming microorganisms. It is thought to arise from the disruption of mucosal integrity in the setting of underlying predisposing factors. Given its high mortality rate, early recognition and prompt management are critical to improving outcomes. We present a rare case of emphysematous gastritis secondary to advanced gastric adenocarcinoma. A limited number of cases describing an association between emphysematous gastritis and malignancy have been reported in the literature, with only a small subset linked to gastric adenocarcinoma. This case underscores the importance of maintaining a high index of suspicion for atypical and malignant etiologies, particularly in patients with nonspecific presentations, as delayed diagnosis may result in rapid clinical deterioration and poor outcomes.

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Publication Details

Journal
Cureus
Published
2026-04-21
DOI
https://doi.org/10.7759/cureus.107492
Primary Topic
Abdominal vascular conditions and treatments
Type
article
Field-Weighted Citation Impact
0.00
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A Rare Association of Emphysematous Gastritis With Gastric Adenocarcinoma: A Case Report and Diagnostic Pitfalls

Garrett Teskey, Steven J Gauerke, Melanie De Shadarevian, Steven Wong et al.
Cureus
Abdominal vascular conditions and treatments
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A Rare Association of Emphysematous Gastritis With Gastric Adenocarcinoma: A Case Report and Diagnostic Pitfalls

Garrett Teskey, Steven J Gauerke, Melanie De Shadarevian, Steven Wong, Wesley Chow
article en

Abstract

Emphysematous gastritis is a rare and life-threatening condition characterized by the presence of gas within the gastric wall, typically caused by gas-forming microorganisms. It is thought to arise from the disruption of mucosal integrity in the setting of underlying predisposing factors. Given its high mortality rate, early recognition and prompt management are critical to improving outcomes. We present a rare case of emphysematous gastritis secondary to advanced gastric adenocarcinoma. A limited number of cases describing an association between emphysematous gastritis and malignancy have been reported in the literature, with only a small subset linked to gastric adenocarcinoma. This case underscores the importance of maintaining a high index of suspicion for atypical and malignant etiologies, particularly in patients with nonspecific presentations, as delayed diagnosis may result in rapid clinical deterioration and poor outcomes.

Cureus
Zero hunger, Good health and well-being
Openalex Percentile: Top 7%
Abdominal vascular conditions and treatments
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