Association of Proximal Neck Angulation and Diameter With Endoleak After Endovascular Aneurysm Repair of Abdominal Aortic Aneurysms

BACKGROUND: Abdominal aortic aneurysm (AAA) is a life-threatening aortic dilation with high rupture mortality. Endovascular aneurysm repair (EVAR) is the preferred minimally invasive treatment, but post-EVAR endoleaks remain a major challenge. AIMS: To investigate the predictive value of suprarenal angle, infrarenal angle, and proximal neck diameter for endoleak following EVAR in AAA patients and their relationships. METHODS: In this retrospective study, 643 consecutive patients undergoing elective EVAR for non-ruptured AAA were grouped into endoleak (n = 179) and non-endoleak (n = 464) groups. For endoleak distribution, type Ia accounted for 10.06% (n = 18), type Ib 4.47% (n = 8), type II 64.25% (n = 115), type III 14.53% (n = 26), type IV 2.79% (n = 5), and type V 3.91% (n = 7). The association between potential predictors and endoleak of any type and the predictive value of suprarenal/infrarenal angle and proximal neck diameter were assessed using logistic analyses and ROC curves. RESULTS: Maximum aneurysm diameter, suprarenal angle, infrarenal angle, and proximal neck diameter were independent predictors for post-EVAR endoleak of any type. The AUCs of suprarenal angle, infrarenal angle, and proximal neck diameter were 0.647, 0.691, and 0.801, respectively. The optimal clinically rounded cut-off values were > 36° (sensitivity: 0.726, specificity: 0.500), > 58° (sensitivity: 0.514, specificity: 0.788), and > 22 mm (sensitivity: 0.704, specificity: 0.761). Combined prediction yielded a superior AUC of 0.851 (sensitivity: 0.816; specificity: 0.746). Greater proximal neck angulation and larger proximal neck diameter increased endoleak risk. CONCLUSION: Suprarenal angle, infrarenal angle, and proximal neck diameter are independent predictors of post-EVAR endoleak. Their combination demonstrates high predictive performance, suggesting that an integrated anatomical assessment can improve preoperative risk stratification.

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Journal
Catheterization and Cardiovascular Interventions
Published
2026-04-21
DOI
https://doi.org/10.1002/ccd.70581
Primary Topic
Aortic aneurysm repair treatments
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article
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article

Association of Proximal Neck Angulation and Diameter With Endoleak After Endovascular Aneurysm Repair of Abdominal Aortic Aneurysms

Jianhang Miao, Xixiang Hu, Zhipeng Hu, Li Tan et al.
Catheterization and Cardiovascular Interventions
Aortic aneurysm repair treatments
article

Association of Proximal Neck Angulation and Diameter With Endoleak After Endovascular Aneurysm Repair of Abdominal Aortic Aneurysms

Jianhang Miao, Xixiang Hu, Zhipeng Hu, Li Tan, Yu He
article en

Abstract

BACKGROUND: Abdominal aortic aneurysm (AAA) is a life-threatening aortic dilation with high rupture mortality. Endovascular aneurysm repair (EVAR) is the preferred minimally invasive treatment, but post-EVAR endoleaks remain a major challenge. AIMS: To investigate the predictive value of suprarenal angle, infrarenal angle, and proximal neck diameter for endoleak following EVAR in AAA patients and their relationships. METHODS: In this retrospective study, 643 consecutive patients undergoing elective EVAR for non-ruptured AAA were grouped into endoleak (n = 179) and non-endoleak (n = 464) groups. For endoleak distribution, type Ia accounted for 10.06% (n = 18), type Ib 4.47% (n = 8), type II 64.25% (n = 115), type III 14.53% (n = 26), type IV 2.79% (n = 5), and type V 3.91% (n = 7). The association between potential predictors and endoleak of any type and the predictive value of suprarenal/infrarenal angle and proximal neck diameter were assessed using logistic analyses and ROC curves. RESULTS: Maximum aneurysm diameter, suprarenal angle, infrarenal angle, and proximal neck diameter were independent predictors for post-EVAR endoleak of any type. The AUCs of suprarenal angle, infrarenal angle, and proximal neck diameter were 0.647, 0.691, and 0.801, respectively. The optimal clinically rounded cut-off values were > 36° (sensitivity: 0.726, specificity: 0.500), > 58° (sensitivity: 0.514, specificity: 0.788), and > 22 mm (sensitivity: 0.704, specificity: 0.761). Combined prediction yielded a superior AUC of 0.851 (sensitivity: 0.816; specificity: 0.746). Greater proximal neck angulation and larger proximal neck diameter increased endoleak risk. CONCLUSION: Suprarenal angle, infrarenal angle, and proximal neck diameter are independent predictors of post-EVAR endoleak. Their combination demonstrates high predictive performance, suggesting that an integrated anatomical assessment can improve preoperative risk stratification.

Catheterization and Cardiovascular Interventions
Zhongshan People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 17%
Aortic aneurysm repair treatments
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