Development and Validation of the Bioanalytical UHPLC–MS/MS Method for the Quantification of Branebrutinib and Metformin: Application for Preclinical Pharmacokinetic Assessments
(2.1-fold), while its elimination rate remained unaltered. Integrated PK/PD studies support further concurrent MTF-BRNB therapies.
Authors
- K Jony Susanna (ORCID: https://orcid.org/0000-0002-1871-9537)
- Sai Jyothi Akula (ORCID: https://orcid.org/0000-0002-6841-7924)
- A. R. Priyadharshni
- P. Radhakrishnanand
- Kale Shyam Shirishkumar
- Dayasagar Rajiv Karkile
Institutions
- National Institute of Pharmaceutical Education and Research (IN)
Publication Details
- Journal
- Biomedical Chromatography
- Published
- 2026-04-20
- DOI
- https://doi.org/10.1002/bmc.70459
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00