9-Keel Unified Theory Series: Paper 10 - The Foundational Paradigm: The TOFD Framework as the Unifying Model for Chronic Disease
This paper is Paper 10 of the 9-Keel Unified Theory Series, establishing the foundational paradigm of the TOFD Framework. It formally defines the central relation of Tissue-Originated Functional Deficiency (TOFD) exceeding homeostatic repair capacity (C) as a unifying theoretical model for chronic disease. The work enshrines the Cell Innocence Principle and supersedes all earlier inconsistent frameworks within the series. Disclaimer: This work is presented for theoretical and academic purposes only and does not constitute medical advice. Individuals with chronic conditions should not alter prescribed medication or care without consulting a licensed physician.
Authors
- FOO SENG ANG
Institutions
- Newcastle University Medicine Malaysia (MY)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2026-04-21
- DOI
- https://doi.org/10.5281/zenodo.19676865
- Primary Topic
- Mental Health and Psychiatry
- Type
- article
- Field-Weighted Citation Impact
- 0.00