Characteristics of Legionnaires’ Disease Cases Hospitalized at a Specialized Infectious Disease Hospital, 2023–2024, with a Focus on Clusters Associated with Travel to a Spa Resort
serogroup 1 in paired serum samples. The most frequently reported symptom was fever (28/32), followed by chills (24/32). Among the 32 confirmed cases, 3 patients died. Two cases were identified as part of a family cluster involving a father and son who had undergone physiotherapy at a balneary resort. Both patients presented with fever and gastrointestinal symptoms, and radiological investigations confirmed mixed pneumonia associated with an intense inflammatory syndrome. In the father's case, hepatic involvement and interstitial nephritis were also identified. Early diagnosis based on epidemiological data, clinical predictive scores, and laboratory investigations would allow timely administration of targeted antibiotic therapy and may contribute to reduced mortality.
Authors
- Andreea Tudor (ORCID: https://orcid.org/0000-0002-0458-1012)
- Laurenţiu Stratan
- Gheorghiță Jugulete (ORCID: https://orcid.org/0000-0002-4193-063X)
- Constanța-Angelica Vișan
- Ana Maria Tudor (ORCID: https://orcid.org/0000-0002-6514-0122)
- Carmen-Cristina Vasile
- Anca Cristina Drăgănescu
- Anca Streinu-Cercel
- Gina Filip
- Daniela Pițigoi
Institutions
- Carol Davila University of Medicine and Pharmacy (RO)
- National Institute of Research and Development for Biological Sciences (RO)
- Institutul National pentru Sanatatea Mamei si Copilului "Alessandrescu-Rusescu" (RO)
Publication Details
- Journal
- Microorganisms
- Published
- 2026-04-21
- DOI
- https://doi.org/10.3390/microorganisms14040935
- Primary Topic
- Legionella and Acanthamoeba research
- Type
- article
- Field-Weighted Citation Impact
- 0.00