SPECT/NIR Fluorescence Bimodal Use of Aza-BODIPY Probe Coupled with Cetuximab for Detection of Cancer: Proof of Concept on a Preclinical Head and Neck Squamous Cell Carcinoma Model

as a promising dual-modality contrast agent for peroperative tumor localization and future fluorescence-guided surgery (FGS), enabling complementary deep-tissue and high-resolution imaging.

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Publication Details

Journal
Journal of Medicinal Chemistry
Published
2026-04-21
DOI
https://doi.org/10.1021/acs.jmedchem.5c03817
Primary Topic
Nanoplatforms for cancer theranostics
Type
article
Field-Weighted Citation Impact
0.00

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article

SPECT/NIR Fluorescence Bimodal Use of Aza-BODIPY Probe Coupled with Cetuximab for Detection of Cancer: Proof of Concept on a Preclinical Head and Neck Squamous Cell Carcinoma Model

Ewen Bodio, Pierre‐Simon Bellaye, A Godard, Lucie Sancey et al.
Journal of Medicinal Chemistry
Nanoplatforms for cancer theranostics
article

SPECT/NIR Fluorescence Bimodal Use of Aza-BODIPY Probe Coupled with Cetuximab for Detection of Cancer: Proof of Concept on a Preclinical Head and Neck Squamous Cell Carcinoma Model

Ewen Bodio, Pierre‐Simon Bellaye, A Godard, Lucie Sancey, Fabien Dalonneau, Benoît Busser, Annika Sickinger, Bertrand Collin, Malorie Privat, Olivier Maury, Christine Goze, Mathieu Moreau, C.-A. Righini, Christol Fabre
article en

Abstract

as a promising dual-modality contrast agent for peroperative tumor localization and future fluorescence-guided surgery (FGS), enabling complementary deep-tissue and high-resolution imaging.

Journal of Medicinal Chemistry
École Normale Supérieure de Lyon (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Université de Bourgogne (FR), Institut Universitaire de France (FR), Centre Hospitalier Universitaire de Grenoble (FR), Centre Georges François Leclerc (FR), Laboratoire de Physique de l'ENS de Lyon (FR), Chimie et Interdisciplinarité, Synthèse, Analyse, Modélisation (FR), Université Grenoble Alpes (FR), Nantes Université (FR)
Agence Nationale de la Recherche, Ministère de l'Enseignement Supérieur et de la Recherche Scientifique, Ligue Contre le Cancer, Centre National de la Recherche Scientifique, Conseil régional de Bourgogne-Franche-Comté, Groupement des Entreprises Françaises dans la lutte contre le Cancer
Openalex Percentile: Top 13%
Nanoplatforms for cancer theranostics
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