Cutaneous Rosai–Dorfman disease involving the left ear responsive to systemic glucocorticoid: a case report
and negative for CD1a and CD207, confirming the diagnosis of cutaneous Rosai-Dorfman disease (CRDD). The initial treatment consisted of oral prednisone acetate combined with methotrexate. Due to limited efficacy and adverse effects, methotrexate was discontinued, and prednisone acetate monotherapy was used. After 2 months, the patient's skin lesions gradually resolved, and hearing improved. This case demonstrates that CRDD involving the ear can lead to hearing recovery following systemic corticosteroid therapy.
Authors
- T T Wang
- Zhuoma Dangzeng
- Xiaoxue Zhuo
- Peiyu Zhou
- Lin Wang
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-04-21
- DOI
- https://doi.org/10.3389/fmed.2026.1797006
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00