Cutaneous Rosai–Dorfman disease involving the left ear responsive to systemic glucocorticoid: a case report

and negative for CD1a and CD207, confirming the diagnosis of cutaneous Rosai-Dorfman disease (CRDD). The initial treatment consisted of oral prednisone acetate combined with methotrexate. Due to limited efficacy and adverse effects, methotrexate was discontinued, and prednisone acetate monotherapy was used. After 2 months, the patient's skin lesions gradually resolved, and hearing improved. This case demonstrates that CRDD involving the ear can lead to hearing recovery following systemic corticosteroid therapy.

Authors

Institutions

Publication Details

Journal
Frontiers in Medicine
Published
2026-04-21
DOI
https://doi.org/10.3389/fmed.2026.1797006
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Cutaneous Rosai–Dorfman disease involving the left ear responsive to systemic glucocorticoid: a case report

T T Wang, Zhuoma Dangzeng, Xiaoxue Zhuo, Peiyu Zhou et al.
Frontiers in Medicine
Histiocytic Disorders and Treatments
article

Cutaneous Rosai–Dorfman disease involving the left ear responsive to systemic glucocorticoid: a case report

T T Wang, Zhuoma Dangzeng, Xiaoxue Zhuo, Peiyu Zhou, Lin Wang
article en

Abstract

and negative for CD1a and CD207, confirming the diagnosis of cutaneous Rosai-Dorfman disease (CRDD). The initial treatment consisted of oral prednisone acetate combined with methotrexate. Due to limited efficacy and adverse effects, methotrexate was discontinued, and prednisone acetate monotherapy was used. After 2 months, the patient's skin lesions gradually resolved, and hearing improved. This case demonstrates that CRDD involving the ear can lead to hearing recovery following systemic corticosteroid therapy.

Frontiers in MedicineVol. 13
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Good health and well-being
Openalex Percentile: Top 19%
Histiocytic Disorders and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.