Quaternary ammonium compounds

Quaternary ammonium compounds QACs are prevalent in many household and personal care products. Research from the Edward Via College of Osteopathic Medicine (VCOM) has shown that QACs, particularly benzalkonium chloride (BAK) and quaternium-12 (DDAC), can cause neural tube defects (NTDs) in mice and may have detrimental effects on human health. Quaternary Ammonium Compounds (QACs) are common chemicals found in over 10,000 household and personal care products. They are also used in medical, food production, and industrial settings. Recent studies by researchers at the Edward Via College of Osteopathic Medicine (VCOM) in Blacksburg, Virginia, USA, have found that QACs can cause neural tube birth defects (NTDs) in mice, calling into question their safety.

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Publication Details

Journal
Open Access Government
Published
2026-04-16
DOI
https://doi.org/10.56367/oag-050-12575
Primary Topic
Environmental Chemistry and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Quaternary ammonium compounds

Terry C. Hrubec
Open Access Government
Environmental Chemistry and Analysis
article

Quaternary ammonium compounds

Terry C. Hrubec
article en

Abstract

Quaternary ammonium compounds QACs are prevalent in many household and personal care products. Research from the Edward Via College of Osteopathic Medicine (VCOM) has shown that QACs, particularly benzalkonium chloride (BAK) and quaternium-12 (DDAC), can cause neural tube defects (NTDs) in mice and may have detrimental effects on human health. Quaternary Ammonium Compounds (QACs) are common chemicals found in over 10,000 household and personal care products. They are also used in medical, food production, and industrial settings. Recent studies by researchers at the Edward Via College of Osteopathic Medicine (VCOM) in Blacksburg, Virginia, USA, have found that QACs can cause neural tube birth defects (NTDs) in mice, calling into question their safety.

Open Access GovernmentVol. 50(1)
Edward Via College of Osteopathic Medicine (US)
Zero hunger
Openalex Percentile: Top 8%
Environmental Chemistry and Analysis
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