Speedy Spirochetes: An Unusually Rapid Progression of Multisystem Manifestations of Syphilis

Syphilis is known as the great imitator due to its variety of clinical presentations. It is also known to have a widely variable timeline for each of its manifestations, although the causes of each of these differing timelines are not yet well established in the literature. The purpose of this case is to highlight a patient with rapidly progressive syphilis, including cutaneous and ocular manifestations, with a brief discussion of factors contributing to timelines and variability of syphilis presentations.

Authors

Publication Details

Journal
Cureus
Published
2026-04-21
DOI
https://doi.org/10.7759/cureus.107450
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Speedy Spirochetes: An Unusually Rapid Progression of Multisystem Manifestations of Syphilis

Yasasvhinie Santharam, Alexis Fazio, Mackenzie Dyrda, Hamza Choudhry et al.
Cureus
Syphilis Diagnosis and Treatment
article

Speedy Spirochetes: An Unusually Rapid Progression of Multisystem Manifestations of Syphilis

Yasasvhinie Santharam, Alexis Fazio, Mackenzie Dyrda, Hamza Choudhry, Sandeep Grover, Jane A Chang
article en

Abstract

Syphilis is known as the great imitator due to its variety of clinical presentations. It is also known to have a widely variable timeline for each of its manifestations, although the causes of each of these differing timelines are not yet well established in the literature. The purpose of this case is to highlight a patient with rapidly progressive syphilis, including cutaneous and ocular manifestations, with a brief discussion of factors contributing to timelines and variability of syphilis presentations.

Cureus
Openalex Percentile: Top 7%
Syphilis Diagnosis and Treatment
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