Coexistent Endometrial and Ovarian Carcinoma: Terminology, Clinicopathological Features, and Clinical Significance

Carcinoma simultaneously involving the endometrium and ovary is encountered frequently enough in clinical practice that guidelines are needed for consistent surgical pathology reporting and patient management. This review will cover the history and terminology of this phenomenon, summarize current practices, and provide a practical reporting framework for daily use. By focusing on conventional surgical pathology parameters, including molecular subtype, while avoiding clonality considerations, it is possible to consistently provide the necessary information to guide treatment. There remain some outstanding issues that require further research, which will be identified and discussed.

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Publication Details

Journal
International Journal of Gynecological Pathology
Published
2026-04-21
DOI
https://doi.org/10.1097/pgp.0000000000001177
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Coexistent Endometrial and Ovarian Carcinoma: Terminology, Clinicopathological Features, and Clinical Significance

C Blake Gilks, Amy Jamieson, Jutta Huvila, Jessica N. McAlpine
International Journal of Gynecological Pathology
Endometrial and Cervical Cancer Treatments
article

Coexistent Endometrial and Ovarian Carcinoma: Terminology, Clinicopathological Features, and Clinical Significance

C Blake Gilks, Amy Jamieson, Jutta Huvila, Jessica N. McAlpine
article en

Abstract

Carcinoma simultaneously involving the endometrium and ovary is encountered frequently enough in clinical practice that guidelines are needed for consistent surgical pathology reporting and patient management. This review will cover the history and terminology of this phenomenon, summarize current practices, and provide a practical reporting framework for daily use. By focusing on conventional surgical pathology parameters, including molecular subtype, while avoiding clonality considerations, it is possible to consistently provide the necessary information to guide treatment. There remain some outstanding issues that require further research, which will be identified and discussed.

International Journal of Gynecological Pathology
University of British Columbia (CA), University of Turku (FI), Turku University Hospital (FI), Vancouver General Hospital (CA)
Openalex Percentile: Top 14%
Endometrial and Cervical Cancer Treatments
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