Recent Advances in 3D-Printed Bioresorbable Vascular Stents: Toward Patient-Specific, Novel-Structured, Functional, and Smart Devices
Bioresorbable vascular stents (BVSs) offer a transformative therapeutic advantage over permanent metal stents by temporarily supporting the vessel and then fully degrading, thereby restoring natural vasomotion and eliminating long-term complications. However, their clinical translation has been hampered by inherent limitations of conventional manufacturing, including restricted material selection, inflexible design, and limited capability for functional integration. Three-dimensional (3D) printing emerges as a pivotal technology to address these challenges, enabling the fabrication of stents with customized architectures, complex structures, and integrated multifunctionality. This review systematically highlights the latest progress in 3D-printed BVSs, focusing on their evolution toward patient-specific, novel-structured, functional, and smart devices. It assesses advanced printing technologies, presents preclinical outcomes and preliminary clinical evidence of 3D-printed BVSs, discusses current challenges, and also provides some future research directions. By framing the current state of the art, this review aims to accelerate the development of next-generation vascular implants.
Authors
- Hugh Zhao
- Sun H
- W.T. Liu (ORCID: https://orcid.org/0000-0003-4885-1675)
- Hanqing Feng
- Guangyao Zhai
- Lizhen Wang
- An-Jung Chen (ORCID: https://orcid.org/0009-0001-4383-1395)
- Qing Liu
- Zhong Chen
- Yujie Zhou
Institutions
- Capital University (US)
- Capital Medical University (CN)
- Dalian Medical University (CN)
- Peking University (CN)
- Beijing Jishuitan Hospital (CN)
- Beijing Luhe Hospital Affiliated to Capital Medical University (CN)
- Beijing Anzhen Hospital (CN)
- Beihang University (CN)
Publication Details
- Journal
- ACS Omega
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1021/acsomega.6c00937
- Primary Topic
- Electrospun Nanofibers in Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China