Recent Advances in 3D-Printed Bioresorbable Vascular Stents: Toward Patient-Specific, Novel-Structured, Functional, and Smart Devices

Bioresorbable vascular stents (BVSs) offer a transformative therapeutic advantage over permanent metal stents by temporarily supporting the vessel and then fully degrading, thereby restoring natural vasomotion and eliminating long-term complications. However, their clinical translation has been hampered by inherent limitations of conventional manufacturing, including restricted material selection, inflexible design, and limited capability for functional integration. Three-dimensional (3D) printing emerges as a pivotal technology to address these challenges, enabling the fabrication of stents with customized architectures, complex structures, and integrated multifunctionality. This review systematically highlights the latest progress in 3D-printed BVSs, focusing on their evolution toward patient-specific, novel-structured, functional, and smart devices. It assesses advanced printing technologies, presents preclinical outcomes and preliminary clinical evidence of 3D-printed BVSs, discusses current challenges, and also provides some future research directions. By framing the current state of the art, this review aims to accelerate the development of next-generation vascular implants.

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Publication Details

Journal
ACS Omega
Published
2026-04-21
DOI
https://doi.org/10.1021/acsomega.6c00937
Primary Topic
Electrospun Nanofibers in Biomedical Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Recent Advances in 3D-Printed Bioresorbable Vascular Stents: Toward Patient-Specific, Novel-Structured, Functional, and Smart Devices

Hugh Zhao, Sun H, W.T. Liu, Hanqing Feng et al.
ACS Omega
Electrospun Nanofibers in Biomedical Applications
article

Recent Advances in 3D-Printed Bioresorbable Vascular Stents: Toward Patient-Specific, Novel-Structured, Functional, and Smart Devices

Hugh Zhao, Sun H, W.T. Liu, Hanqing Feng, Guangyao Zhai, Lizhen Wang, An-Jung Chen, Qing Liu, Zhong Chen, Yujie Zhou
article en

Abstract

Bioresorbable vascular stents (BVSs) offer a transformative therapeutic advantage over permanent metal stents by temporarily supporting the vessel and then fully degrading, thereby restoring natural vasomotion and eliminating long-term complications. However, their clinical translation has been hampered by inherent limitations of conventional manufacturing, including restricted material selection, inflexible design, and limited capability for functional integration. Three-dimensional (3D) printing emerges as a pivotal technology to address these challenges, enabling the fabrication of stents with customized architectures, complex structures, and integrated multifunctionality. This review systematically highlights the latest progress in 3D-printed BVSs, focusing on their evolution toward patient-specific, novel-structured, functional, and smart devices. It assesses advanced printing technologies, presents preclinical outcomes and preliminary clinical evidence of 3D-printed BVSs, discusses current challenges, and also provides some future research directions. By framing the current state of the art, this review aims to accelerate the development of next-generation vascular implants.

ACS OmegaVol. 11(17)
Capital University (US), Capital Medical University (CN), Dalian Medical University (CN), Peking University (CN), Beijing Jishuitan Hospital (CN), Beijing Luhe Hospital Affiliated to Capital Medical University (CN), Beijing Anzhen Hospital (CN), Beihang University (CN)
National Key Research and Development Program of China
Openalex Percentile: Top 22%
Electrospun Nanofibers in Biomedical Applications
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