Fluorogenic Heterodimers Enable Rapid Fluorescence Lifetime Imaging of Prostate-Specific Membrane Antigen-Positive Tumors
achieved rapid, wash-free staining with high tumor-to-background contrast. In summary, this work establishes a versatile strategy for fast activatable NIR probes and demonstrates its potential for precise real-time imaging in prostate cancer surgery and pathology.
Authors
- Hongchuang Xu (ORCID: https://orcid.org/0009-0004-2400-9621)
- Xing Yang (ORCID: https://orcid.org/0000-0001-5186-4990)
- Jingming Zhang (ORCID: https://orcid.org/0000-0002-0961-934X)
- X S Li
- Zhuang Shao
- Y Yan
- Xuejiao Chen
- Ning Zhang
Institutions
- University of Medical Sciences and Technology (SD)
- Prudential Financial (United States) (US)
- Peking University (CN)
- National Medical Products Administration (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- scPharmaceuticals (United States) (US)
- Osaka International Cancer Institute (JP)
- Translational Research in Oncology (FR)
- Peking University People's Hospital (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- ACS Sensors
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1021/acssensors.5c04720
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing Municipal Natural Science Foundation