Probing the hAGO2-siRNA Interactions: A Molecular Dynamics Study on the Impact of Chemical Modifications in the Seed Region

)-GNA, and ANA, providing critical insights for the design and development of next-generation siRNA-based therapeutics.

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Publication Details

Journal
Journal of Chemical Information and Modeling
Published
2026-04-21
DOI
https://doi.org/10.1021/acs.jcim.5c02975
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
0.00

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article

Probing the hAGO2-siRNA Interactions: A Molecular Dynamics Study on the Impact of Chemical Modifications in the Seed Region

Journal of Chemical Information and Modeling
RNA Interference and Gene Delivery
article

Probing the hAGO2-siRNA Interactions: A Molecular Dynamics Study on the Impact of Chemical Modifications in the Seed Region

article en

Abstract

)-GNA, and ANA, providing critical insights for the design and development of next-generation siRNA-based therapeutics.

Journal of Chemical Information and ModelingVol. 66(9)
Indian Institute of Technology Kharagpur (IN)
Department of Science and Technology, Ministry of Science and Technology, India, Indian Institute of Technology Kharagpur, Science and Engineering Research Board
Zero hunger
Openalex Percentile: Top 22%
RNA Interference and Gene Delivery
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Probing the hAGO2-siRNA Interactions: A Molecular Dynamics Study on the Impact of Chemical Modifications in the Seed Region · Journal of Chemical Information and Modeling (2026) | TGRS Research Map | TGRS