Single-center clinical analysis of hybrid aortic arch repair for aortic arch lesions

Objective: To evaluate the safety and short-to-mid-term efficacy of hybrid aortic arch repair (HAR) within a structured, anatomy- and risk-based decision-making framework for heterogeneous aortic arch lesions. Methods: = 27). Type I involved debranching with staged Zone 0 thoracic endovascular aortic repair (TEVAR), Type II consisted of total arch replacement with stented elephant trunk followed by TEVAR, and Type IV used cervical bypass with one-stage Zone 2 TEVAR. All decisions were confirmed by a multidisciplinary team. Results: All procedures were technically successful, with no intraoperative or 30-day mortality. Type I HAR showed the shortest operative time and least blood loss, whereas Type II had the highest surgical complexity and longest recovery. Postoperative complications were minor, and no stroke, renal failure, or permanent organ injury occurred. During a median follow-up of 18 months (range, 6-36 months), no aortic-related death, endoleak, reintervention, or branch vessel occlusion occurred. Aorta-related survival and freedom from reintervention were both 100%. Conclusion: Individualized HAR guided by anatomical features and patient risk provides a safe and effective treatment for complex aortic arch lesions, particularly in high-risk patients unsuitable for open surgery.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-04-21
DOI
https://doi.org/10.3389/fcvm.2026.1797260
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
Field-Weighted Citation Impact
0.00

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article

Single-center clinical analysis of hybrid aortic arch repair for aortic arch lesions

Quanhua Pan, You Wang, Lijuan Zhang, Yang Gao et al.
Frontiers in Cardiovascular Medicine
Aortic Disease and Treatment Approaches
article

Single-center clinical analysis of hybrid aortic arch repair for aortic arch lesions

Quanhua Pan, You Wang, Lijuan Zhang, Yang Gao, Zhiwei Xu, Chuanzhang Xu
article en

Abstract

Objective: To evaluate the safety and short-to-mid-term efficacy of hybrid aortic arch repair (HAR) within a structured, anatomy- and risk-based decision-making framework for heterogeneous aortic arch lesions. Methods: = 27). Type I involved debranching with staged Zone 0 thoracic endovascular aortic repair (TEVAR), Type II consisted of total arch replacement with stented elephant trunk followed by TEVAR, and Type IV used cervical bypass with one-stage Zone 2 TEVAR. All decisions were confirmed by a multidisciplinary team. Results: All procedures were technically successful, with no intraoperative or 30-day mortality. Type I HAR showed the shortest operative time and least blood loss, whereas Type II had the highest surgical complexity and longest recovery. Postoperative complications were minor, and no stroke, renal failure, or permanent organ injury occurred. During a median follow-up of 18 months (range, 6-36 months), no aortic-related death, endoleak, reintervention, or branch vessel occlusion occurred. Aorta-related survival and freedom from reintervention were both 100%. Conclusion: Individualized HAR guided by anatomical features and patient risk provides a safe and effective treatment for complex aortic arch lesions, particularly in high-risk patients unsuitable for open surgery.

Frontiers in Cardiovascular MedicineVol. 13
Nanjing Medical University (CN)
Nanjing Medical University
Openalex Percentile: Top 21%
Aortic Disease and Treatment Approaches
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