A Biohybrid Catalyst for Cross-Coupling Reactions That Contains Pd/P.yeei@ORMOSIL

This study demonstrates the feasibility of encapsulating Paracoccus yeei VKM B-3302 cells, which contain palladium nanoparticles, within an organosilicon matrix synthesized using the sol–gel method. The resulting organosilicon material is characterized by a well-developed porous structure and a high specific surface area, ensuring the formation of a catalytic system with accessible active sites. Kinetic studies of the Mizoroki–Heck reaction showed that, although encapsulating the Pd/P. yeei catalyst in an organosilicon matrix slightly decreases its initial reaction rate, it increases the selectivity of the process and reduces the leaching of the active metal during repeated use. These results suggest the potential of encapsulating microorganisms containing metal nanoparticles in organosilicon materials to create stable hybrid catalytic systems.