Heart Transplantation on Temporary Mechanical Circulatory Support: A Single-Center Study (2010–2024)

Background: Temporary mechanical circulatory support (tMCS) is increasingly used to stabilize patients in cardiogenic shock as a bridge-to-transplant. While this strategy facilitates listing and organ allocation in critically ill patients, its effect on post-transplant outcomes remains incompletely defined. Methods: -test and chi-square tests were used for comparisons. Results: < 0.01). Resternotomy rates were similar. Patients bridged with Impella or transitioned from extracorporeal membrane oxygenation to right ventricular-assist device (RVAD) had better outcomes than those transplanted directly from ECLS. Conclusion: HTX in tMCS-supported patients is feasible but associated with significantly higher early and mid-term mortality. The type of preoperative support and transition strategy may impact outcomes. Tailored bridging concepts and early conversion to durable or RVAD-based support warrant further investigation.

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Publication Details

Journal
The Thoracic and Cardiovascular Surgeon
Published
2026-04-21
DOI
https://doi.org/10.1055/a-2858-4481
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
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article

Heart Transplantation on Temporary Mechanical Circulatory Support: A Single-Center Study (2010–2024)

Vincent Hettlich, Freya Sophie Jenkins, Raphael Phinicarides, B. Ramadani et al.
The Thoracic and Cardiovascular Surgeon
Mechanical Circulatory Support Devices
article

Heart Transplantation on Temporary Mechanical Circulatory Support: A Single-Center Study (2010–2024)

Vincent Hettlich, Freya Sophie Jenkins, Raphael Phinicarides, B. Ramadani, Charlotte Boettger, H Aubin, Tobias Zeus, Artur Lichtenberg, Fabian Voß, Udo Boeken, Nikolaos Kalampokas
article en

Abstract

Background: Temporary mechanical circulatory support (tMCS) is increasingly used to stabilize patients in cardiogenic shock as a bridge-to-transplant. While this strategy facilitates listing and organ allocation in critically ill patients, its effect on post-transplant outcomes remains incompletely defined. Methods: -test and chi-square tests were used for comparisons. Results: < 0.01). Resternotomy rates were similar. Patients bridged with Impella or transitioned from extracorporeal membrane oxygenation to right ventricular-assist device (RVAD) had better outcomes than those transplanted directly from ECLS. Conclusion: HTX in tMCS-supported patients is feasible but associated with significantly higher early and mid-term mortality. The type of preoperative support and transition strategy may impact outcomes. Tailored bridging concepts and early conversion to durable or RVAD-based support warrant further investigation.

The Thoracic and Cardiovascular Surgeon
Düsseldorf University Hospital (DE), Heinrich Heine University Düsseldorf (DE)
Openalex Percentile: Top 21%
Mechanical Circulatory Support Devices
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